TY - JOUR AU - Feshchenko, Yu.I. AU - Gumeniuk, M.I. AU - Lynnyk, М.І. AU - Dziublyk, O.Ya. AU - Kuzhko, M.M. AU - Tereshkovych, О.V. AU - Khmel, O.V. AU - Panashchuk, I.O. AU - Yashchenko, M.V. AU - Denysov, О.S. AU - Sprynsian, Т.А. PY - 2021/12/27 Y2 - 2024/03/28 TI - Inhaled antiseptics and inhaled antiviral non-prescription drugs in the prevention of ARVI, in particular COVID-19: an epidemiological study JF - Infusion & Chemotherapy JA - IC VL - IS - 4 SE - ORIGINAL STUDIES DO - 10.32902/2663-0338-2021-4-5-15 UR - https://infusion-chemotherapy.com/index.php/journal/article/view/294 SP - 5-15 AB - BACKGROUND. The article presents the results of a continuous, cross-sectional, non-interventional, multicenter retrospective epidemiological study, which included cases of 3443 participants. Questionnaires and rapid test for antibodies to SARS-CoV-2 were used to collect data.OBJECTIVE. To determine the relationship between the systematic use of additional drugs for the prevention of COVID-19, including inhaled antiseptics and inhaled antiviral drugs, separately and in combination with other drugs, and the risk of developing of coronavirus disease (COVID-19).RESULTS AND DISCUSSION. 396 participants (11.8 %) took inhaled antiseptics in any period since March 2020, and 410 participants (12.2 %) took inhaled antivirals. A statistically significant protective relationship between episode of COVID-19 when taking inhaled antiseptics and inhaled antiviral drugs (risk ratio 0.901; 95 % confidence interval 0.856-0.948) was determined.CONCLUSIONS. The use of inhaled antiseptics and inhaled antiviral drugs as additional methods of prevention of COVID-19 has shown a statistically significant effect not only on reducing the risk of COVID-19, but different combinations of inhaled antiseptics or inhaled antiviral drugs with other drug groups as additional methods of preventing COVID-19 had a statistically significant protective relationship with the episode of the disease, with the severity of COVID-19 and with the need for hospitalization. ER -