@article{Shevchenko_Pohorielova_2019, title={Issues of Tuberculosis Drug-Resistance in Kharkiv Region and in Ukraine}, url={https://infusion-chemotherapy.com/index.php/journal/article/view/112}, DOI={10.32902/2663-0338-2019-3-24-28}, abstractNote={<p><strong>Background.</strong> Multidrug-resistant tuberculosis and extensively drug-resistant tuberculosis remain severe epidemic problems in the world. That’s why the purpose of our study was to investigate the dynamics of the incidence of multidrug-resistant and extensively drug-resistant tuberculosis, the structure of cases and the effectiveness of treatment in this category of patients in the Kharkiv region and in Ukraine.</p> <p><strong>Materials and methods.</strong> To perform the study, data from reporting forms No. 4-2 (TB 07 – MDR TB), No. 8-6 (TB 08) and data from analytical and statistical reference books “Tuberculosis in Ukraine” were used. Statistical processing of information was carried out using Statistica 7.0, Microsoft Office Excel 2007.</p> <p><strong>Results.</strong> We found a relatively consistently high incidence rate, prevalence of tuberculosis recurrences among patients with drug-resistant tuberculosis, an increase in the proportion of extensively-drug resistance in patients with treatment failure and interrupted treatment, and low effectiveness of treatment of multidrug-resistant and extensively drug-resistant tuberculosis in patients with repeated cases of treatment.</p> <p><strong>Conclusions.</strong> The obtained data once again emphasizes the need for the selection of adequate schemes for antituberculosis chemotherapy and control of anti-tuberculosis drugs.</p&gt;}, number={3}, journal={Infusion & Chemotherapy}, author={Shevchenko, O.S. and Pohorielova, O.O.}, year={2019}, month={Nov.}, pages={24-28} }