The relevance of infusion and transfusion therapy in obstetric practice

  • G.N. Indiaminova Samarkand State Medical Institute, Samarkand, Uzbekistan


Objective. To improve the outcomes of treatment of massive bleeding in obstetrics in combination with infusion-transfusion therapy (ITT).

Materials and methods. Clinical and laboratory study of 16 women with bleeding in the early postpartum period (EPP).

Results and discussion. We examined 16 women with bleeding for various reasons in the EPP. Of these, in 4 (25 %) women, the cause of bleeding in the postpartum period was trauma to the birth canal, in 2 (12.5 %) women there was dense attachment of the placenta, in 3 (18.75 %) women, bleeding in the EPP was observed due to the remainder of parts placenta and membranes in the uterine cavity, 3 (18.75 %) women had uterine hypotension due to an overstretched uterus due to the birth of a large fetus, twins and prolonged labor, 1 (6.25 %) women had gestosis and a history uterine fibroids. Patients with massive bleeding, regardless of the method of delivery, were characterized by a significant increase in the incidence of coagulopathy as a cause of postpartum hemorrhage (more than 18.75 %). Factors increasing the risk of massive blood loss were uterine fibroids (6.25 %) and gestosis (12.5 %). The estimate of blood loss, calculated with an additional coefficient (with the visual method +30 % of the estimated value, with the gravimetric method +20 %), corresponded to the objective data as much as possible. Underestimation of blood loss occurred in less than half of cases (43.75 %) and did not exceed 100 ml. Presenting the volume of bleeding as a percentage of body weight proved to be an effective way to combat underestimation of obstetric blood loss, which indicated the timely initiation of ITT. The use of transfusion agents (fresh frozen plasma and erythromass in 56.25 % of cases) allowed to avoid severe coagulopathic disorders, prevented severe anemia, and neutralized hemoconcentration deviations.

Conclusions. The effectiveness of the ITT standard in massive postpartum hemorrhage is confirmed by the absence of maternal mortality, cases of severe anemia in the postpartum period, significant differences in the number of postpartum infectious and inflammatory complications and the timing of patients’ discharge.

Keywords: early postpartum hemorrhage, infusion-transfusion therapy, blood loss, coagulopathy, early postpartum period.
How to Cite
Indiaminova , G. (2020). The relevance of infusion and transfusion therapy in obstetric practice. Infusion & Chemotherapy, (3.1), 36-37.
Materials of IV International Congress of infusion therapy