Application of sorbitol-based infusion preparation for normalization of biochemical indicators in the blood in surgery patients with direct rectal cancer

  • Ye.S. Varivoda State Institution “Institute of Blood Pathology and Transfusion Medicine of the National Academy of Medical Sciences of Ukraine”, Lviv, Ukraine
  • I.Ya. Orishchin State Institution “Institute of Blood Pathology and Transfusion Medicine of the National Academy of Medical Sciences of Ukraine”, Lviv, Ukraine
  • V.M. Lutsiv State Institution “Institute of Blood Pathology and Transfusion Medicine of the National Academy of Medical Sciences of Ukraine”, Lviv, Ukraine
  • V.Ye. Varivoda State Institution “Institute of Blood Pathology and Transfusion Medicine of the National Academy of Medical Sciences of Ukraine”, Lviv, Ukraine
  • B.R. Dzis State Institution “Institute of Blood Pathology and Transfusion Medicine of the National Academy of Medical Sciences of Ukraine”, Lviv, Ukraine
  • V.Ye. Chaban State Institution “Institute of Blood Pathology and Transfusion Medicine of the National Academy of Medical Sciences of Ukraine”, Lviv, Ukraine
  • R.P. Dzis State Institution “Institute of Blood Pathology and Transfusion Medicine of the National Academy of Medical Sciences of Ukraine”, Lviv, Ukraine
  • Ye.Р. Karpovich State Institution “Institute of Blood Pathology and Transfusion Medicine of the National Academy of Medical Sciences of Ukraine”, Lviv, Ukraine

Abstract

Objective. To study the effect of intravenous infusions of the complex drug Rheosorbilaсt polyfunctional action on the biochemical parameters in the blood in operated patients with rectal cancer after anterior resection of the rectum in the early postoperative period.

Materials and methods. The study of biochemical parameters in the blood of 30 patients with colorectal cancer was performed in the first days after surgery, and on the 2nd, 3rd, 5th day after administration of the drug Rheosorbilact. The drug was administered intravenously at a rate of 40 drops per minute. The daily dose of Rheosorbilact was 800.0 ml.

Results. As a result of biochemical studies in patients with colorectal cancer, in the first days after anterior resection of the rectum revealed a decrease in total protein, increased concentrations of urea, creatinine and blood glucose. To correct the biochemical parameters in the blood of such patients immediately after surgery was administered intravenous infusion of Rheosorbilact. After repeated intravenous infusions of Rheosorbilact for 5 days, a significant increase in total protein content, a significant decrease in the concentration of urea, creatinine and blood glucose in the operated patients was found. Therefore, multiple intravenous infusions of the complex drug Rheosorbilact multifunctional action lead to the normalization of biochemical parameters in the blood.

Conclusions. In patients with rectal cancer after anterior resection of the rectum in the first days after surgery revealed a decrease in total protein, increased concentrations of urea, creatinine and blood glucose. Repeated intravenous infusions of the complex drug Rheosorbilact multifunctional action normalize the biochemical parameters in the blood in operated patients with rectal cancer after anterior resection of the rectum in the early postoperative period. Rheosorbilact infusion is recommended for widespread medical use in such patients, especially in the early postoperative period.

Keywords: cancer patients, anterior resection of the rectum, infusion drug Rheosorbilact, biochemical parameters of blood.
Published
2020-10-21
How to Cite
Varivoda, Y., Orishchin, I., Lutsiv, V., Varivoda, V., Dzis, B., Chaban, V., Dzis, R., & Karpovich, Y. (2020). Application of sorbitol-based infusion preparation for normalization of biochemical indicators in the blood in surgery patients with direct rectal cancer. Infusion & Chemotherapy, (3.1), 17-17. https://doi.org/10.32902/2663-0338-2020-3.1-13
Section
Materials of IV International Congress of infusion therapy