The effect of L-arginine and L-carnitine preparations on the dynamics of indicators of endogenous intoxication and systemic capillary leakage in patients with a complicated course of diabetes
ABSTRACT. In order to study the effect of drugs containing L-arginine and L-carnitine on the indicators of endogenous intoxication and systemic capillary leakage in patients with complicated diabetes mellitus, 30 patients with diabetic ketoacidosis, representative by age, sex, comorbidity were examined. Among the patients were 13 men and 17 women, with a mean age of 52.36±2.87 years. It is shown that the use of the drug Tivorel in the treatment of such patients reduces the severity of systemic capillary leakage syndrome and manifestations of endogenous intoxication.
International Diabetes Federation (IDF). Available at: http://www.idf.org.
IDF Diabetes Atlas 2021 – 10th edition. Available at: www.diabetesatlas.org.
Shlapak I.P., Halushko O.A. Experience in the use of Tivortin in the complex treatment of diabetic foot syndrome. Clinical surgery. 2011; 2 (815): 61-64.
Boyko V.V., Biletskyi S.V., Kazantseva T.V., Petrynych O.A. Metabolic effects of Corvitin and Tivortin in patients with hypertension combined with stable coronary heart disease and type 2 diabetes. Achievements of clinical and experimental medicine. 2018; 1: 50-54.
Shved M.I., Grynchuk U.I., Pigovska Yu.A., Shved A.M., Heryak S.M. Endothelial protective efficacy of Tivorel in patients with diabetic retinopathy. Achievements of clinical and experimental medicine. 2018; 2: 194-201.
Tashchuk V.K. Effectiveness of L-arginine and L-carnitine in the treatment of cardiovascular and comorbid pathology. Health of Ukraine. 2020, 3: 41.
Mostovoi Yu.M., Rasputina L.V., Didenko D.V., Rasputin V.V., Mezhievskaya I.A., Bronyuk A.V. Acute myocardial infarction in patients with diabetes mellitus: possibility and expediency of cardioprotection. Heart and blood vessels. 2018; 4: 5-10.
Polishchuk M.E., Halushko O.A., Gumeniuk M.I., Trishchynska M.A. Infusion therapy in neurology and neurosurgery. Kyiv: Book-plus, 2020. 304 p.
Speransky I.I., Samoilenko G.E., Lobacheva M.V. Integral indices of intoxication as criteria for assessing the severity of endogenous intoxication, its complications and the effectiveness of treatment. Acute and emergency conditions in a doctor’s practice. 2009; 6 (19): 23-29.
Bulatov R.D. Application of integral two-frequency impedance measurement in clinical monitoring in patients with destructive pancreatitis. Anesthesiology and resuscitation. 2012; 3: 59-62.
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