Modern possibilities of infusion therapy in patients with diabetic ketoacidosis

  • O. A. Halushko National Medical Academy of Postgraduate Education named after P. L. Shupyk, Kyiv, Ukraine https://orcid.org/0000-0001-7027-8110
  • S. I. Babak Kyiv Regional Clinical Hospital, Kyiv, Ukraine
  • S. M. Nedashkivskyi National Medical Academy of Postgraduate Education named after P. L. Shupyk, Kyiv, Ukraine https://orcid.org/0000-0002-7069-4517
  • S. P. Dyachenko National Medical Academy of Postgraduate Education named after P. L. Shupyk, Kyiv, Ukraine

Abstract

ABSTRACT. The mechanisms of development and clinical manifestations of diabetic ketoacidosis (DKA) are analyzed in the article, the prospects of the use of xylitol-based infusions in the treatment of DKA are discussed. The authors also presented the infusion therapy program and their own experience with the use of Xylat solution. It has been shown that the use of Xylat can have a positive effect on various parts of the pathological process – from elimination of dehydration to the correction of disorders of acid-base status (ABS). Xylat should be started with the first signs of DKA, even in the absence or low severity of ketonuria according to the nitroprusside test. This tactic makes it possible to normalize ABS more quickly and reduce the overall amount of infusion therapy.

Keywords: diabetes mellitus, diabetic ketoacidosis, infusion therapy, Xylat.

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Published
2020-10-10
How to Cite
Halushko, O. A., Babak, S. I., Nedashkivskyi, S. M., & Dyachenko, S. P. (2020). Modern possibilities of infusion therapy in patients with diabetic ketoacidosis. Infusion & Chemotherapy, (3), 11-17. https://doi.org/10.32902/2663-0338-2020-3-11-17
Section
REVIEW ARTICLE

Author Biographies

O. A. Halushko, National Medical Academy of Postgraduate Education named after P. L. Shupyk, Kyiv, Ukraine

Halushko Oleksandr Anatoliiovych
Professor of the Department of Anesthesiology and Intensive Therapy
Doctor of medicine.
9, Dorogozhytska st., Kyiv, 04112, Ukraine.
E‑mail: o.halushko@ukr.net

S. I. Babak, Kyiv Regional Clinical Hospital, Kyiv, Ukraine

Babak Serhii Ivanovych
Head of the Department of Intensive Therapy
1, Bahhovutivska st., Kyiv, 04107, Ukraine.

S. M. Nedashkivskyi, National Medical Academy of Postgraduate Education named after P. L. Shupyk, Kyiv, Ukraine

Nedashkivskyi Serhii Mykhailovych
Associate Professor of the Department of Anesthesiology and Intensive Therapy
PhD.
9, Dorogozhytska st., Kyiv, 04112, Ukraine.

S. P. Dyachenko, National Medical Academy of Postgraduate Education named after P. L. Shupyk, Kyiv, Ukraine

Dyachenko Serhii Petrovych
Doctor of the Department of Intensive Therapy
1, Bahhovutivska st., Kyiv, 04107, Ukraine.